Randomized controlled trial of a treatment for anorexia and bulimia nervosa
Identifieur interne : 000B25 ( Main/Exploration ); précédent : 000B24; suivant : 000B26Randomized controlled trial of a treatment for anorexia and bulimia nervosa
Auteurs : Cecilia Bergh [Suède] ; Ulf Brodin [Suède] ; Greger Lindberg [Suède] ; Per Södersten [Suède]Source :
- Proceedings of the National Academy of Sciences of the United States of America [ 0027-8424 ] ; 2002.
Abstract
Evidence for the effectiveness of existing treatments of patients
with eating disorders is weak. Here we describe and evaluate a method
of treatment in a randomized controlled trial. Sixteen patients,
randomly selected out of a group composed of 19 patients with anorexia
nervosa and 13 with bulimia nervosa, were trained to eat and recognize
satiety by using computer support. They rested in a warm room after
eating, and their physical activity was restricted. The patients in the
control group (
Url:
DOI: 10.1073/pnas.142284799
PubMed: 12082182
PubMed Central: 123167
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Evidence for the effectiveness of existing treatments of patients
with eating disorders is weak. Here we describe and evaluate a method
of treatment in a randomized controlled trial. Sixteen patients,
randomly selected out of a group composed of 19 patients with anorexia
nervosa and 13 with bulimia nervosa, were trained to eat and recognize
satiety by using computer support. They rested in a warm room after
eating, and their physical activity was restricted. The patients in the
control group (<italic>n</italic>
= 16) received no
treatment. Remission was defined by normal body weight
(anorexia), cessation of binge eating and purging (bulimia), a normal
psychiatric profile, normal laboratory test values, normal eating
behavior, and resumption of social activities. Fourteen patients went
into remission after a median of 14.4 months (range 4.9–26.5) of
treatment, but only one patient went into remission while waiting for
treatment (<italic>P</italic>
= 0.0057). Relapse is considered a
major problem in patients who have been treated to remission. We
therefore report results on a total of 168 patients who have entered
our treatment program. The estimated rate of remission was 75%, and
estimated time to remission was 14.7 months (quartile range 9.6 ≥
32). Six patients (7%) of 83 who were treated to remission
relapsed, but the others (93%) have remained in remission for 12
months (quartile range 6–36). Because the risk of relapse is
maximal in the first year after remission, we suggest that most
patients treated with this method recover.</p>
</div>
</front>
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<tree><country name="Suède"><noRegion><name sortKey="Bergh, Cecilia" sort="Bergh, Cecilia" uniqKey="Bergh C" first="Cecilia" last="Bergh">Cecilia Bergh</name>
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<name sortKey="Brodin, Ulf" sort="Brodin, Ulf" uniqKey="Brodin U" first="Ulf" last="Brodin">Ulf Brodin</name>
<name sortKey="Lindberg, Greger" sort="Lindberg, Greger" uniqKey="Lindberg G" first="Greger" last="Lindberg">Greger Lindberg</name>
<name sortKey="Sodersten, Per" sort="Sodersten, Per" uniqKey="Sodersten P" first="Per" last="Södersten">Per Södersten</name>
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